Archive of past Lupus Innovation Award (LIA)
2021 Funded Grants
Identification of new genes that restrict TLR7 responses to self nucleic acids
Gregory Barton, PhD
University of California, Berkeley
Role of novel metabolite-receptor pathway in protection from lupus
Jason Cyster, PhD
University of California, San Francisco
Linking the microbiome and the B cell repertoire to lupus nephritis
Bart Lambrecht, MD, PhD
VIB-UGent Center for Inflammation Research
Targeted regulatory T cells (Tregs) to treat lupus nephritis
Joshua Ooi, PhD
Monash University
2020 Funded Grants
Erythroid mitochondrial dysfunction in lupus pathogenesis
Simone Caielli, PhD
Weill Cornell Medical College
cGAMP as an immune transmitter of the interferon response
Keith B. Elkon, MD
University of Washington
Targeting a novel population of innate-like CD8+ Treg in lupus
Vipin Kumar, PhD
The Regents of University of California, San Diego
Modeling cognitive impairment in patients with systemic lupus erythematosus
Zahi Touma, MD, PhD
University Health Network
Targeting mTORC2 for lupus treatment
Hu Zeng, PhD
Mayo Clinic, Rochester, MN
2019 Funded Grants
The role of microglial subsets in driving neuropsychiatric symptoms of SLE
Carla Cuda, PhD
Northwestern University Feinberg School of Medicine
Circadian dysregulation of immune function in SLE
Anne Davidson, MBBS
Donald and Barbara Zucker School of Medicine at Hofstra/Northwell and Feinstein Institutes for Medical Research
Contribution of dysregulated granulopoiesis to SLE pathogenesis
Neelakshi Jog, PhD
Oklahoma Medical Research Foundation
Establishing the role of apoptosis and mtDNA in the pathobiology of lupus
Benjamin Kile, PhD
Monash University, Clayton, Australia
New mechanisms for thrombosis and atherosclerosis in SLE and APS
Yee Ling Wu, PhD
Loyola University Chicago Health Sciences Division
2018 Funded Grants
Ferroptosis as a novel driver of inflammation in lupus nephritis
Erika Boesen, PhD
University of Nebraska Medical Center
Lymphatic regulation and photosensitivity
Theresa Lu, MD, PhD
The Hospital for Special Surgery
Age-associated B cells in autoimmune lupus
Kevin Nickerson, PhD
University of Pittsburgh
Genetically engineering regulatory T cells to treat SLE
Joshua Ooi, PhD
School of Clinical Sciences, Monash University
Examining the role of T cell exhaustion in lupus pathogenesis
Jeremy Tilstra, MD, PhD
University of Pittsburgh
Epigenetic regulation of Il2 by ATF7ip – implications for SLE
Michael Waterfield, MD, PhD
University of California, San Francisco
2017 Funded Grants
Immunotargeting of T follicular helper (Tfh) cells for SLE treatment
Andre Ballesteros-Tato, PhD
University of Alabama at Birmingham
Unexpected role(s) for IRF5 risk variants in SLE pathogenesis
Betsy Jo Barnes, PhD
The Feinstein Institute for Medical Research
Neutrophil elastase as a therapeutic target in lupus
Jason S. Knight, MD, PhD
University of Michigan Medical School
Characterization of chemokine producing effector B cells in SLE
Frances E. Lund, PhD
University of Alabama at Birmingham
Targeting nicotinic receptors to reduce inflammation associated with SLE
Keisa Williams Mathis, PhD
University of Texas Health Science Center at Fort Worth
Targeting immunometabolism and co-stimulation in combination therapies in lupus
Laurence Morel, PhD
University of Florida College of Medicine
Regulation of CD11c+Tbet+ B cells in lupus
Alessandra B. Pernis, MD
The Hospital for Special Surgery
Mechanisms of the autoimmune germinal center response in SLE
Ziaur Rahman, MD, PhD
Pennsylvania State University College of Medicine
Targeting EZH2 in lupus
Amr Sawalha, MD
University of Pittsburgh
2016 Funded Grants
Autophagy components and B cell activation during SLE
Mridu Acharya, PhD
Benaroya Research Institute at Virginia Mason
Anti-BDCA 2-targeted therapy for SLE
Natalia Giltiay, PhD
University of Washington
B cell-intrinsic cytokine reg of spontaneous germinal ctr formation in SLE
Shaun Jackson MD, PhD
Seattle Children’s Hospital
Multi-level biomarkers for psychiatric disorders in pediatric lupus
Andrea Knight, MD, FRCPC
The Hospital for Sick Children
Targeting type II NKT cells for a novel therapeutic in lupus
Vipin Kumar, PhD
University of California, San Diego
Impaired mitochondrial clearance in systemic lupus erythematosus
Christian Lood, PhD
University of Washington
Mitochondria, caspases and type I interferons in autoimmunity
Anthony Rongvaux, PhD
Fred Hutchinson Cancer Research Center
Cathepsin S inhibitor-modified Treg cells mitigate murine SLE
Guo-Ping Shi, ScD
Brigham and Women’s Hospital
Oxidized mitochondrial DNA employs APEX1 in neutrophils to control lupus
Zhiqiang Zhang, PhD
The Methodist Hospital Research Institute
A novel approach for treating lupus by inhibiting Fli1 transcription factor
John Zhang, PhD
Medical University of South Carolina
2015 Funded Grants
Role of infection in obstetric antiphospholipid syndrome
Vikki M. Abrahams, PhD
Yale University
Therapeutic selective targeting of BAFF receptors
Julio A. Camarero, PhD
USC/University of Southern California
Pesticides and chemical exposures, DNA methylation, and SLE phenotypes
Lindsey Ann Criswell, MD, MPH
University of California, San Francisco
Bacterial amyloids from biofilms break tolerance in lupus
Stefania Gallucci, MD
Temple University
Understanding the pathway regulated by the lupus susceptibility gene Ets1
Lee Ann Garrett-Sinha, PhD
The Research Foundation for The SUNY University at Buffalo
Repopulation of tolerogenic B cells post B cell depletion therapy in lupus
Hui-Chen Hsu, PhD
The University of Alabama at Birmingham
IDO2, a novel therapeutic target for the treatment of lupus
Laura Mandik-Nayak, PhD
Lankenau Institute for Medical Research
Tolerogenic dendritic cells in human lupus
Timothy B. Niewold, MD
New York University School of Medicine
Sex disparity in lupus is driven by putative X-linked genes
Robert Hal Scofield, MD
Oklahoma Medical Research Foundation
Cross sectional and longitudinal studies of immune complexes in SLE
Barbara J. Vilen, PhD
The University of North Carolina at Chapel Hill
A free website for discovering non-coding lupus-associated variant function
Matthew T. Weirauch, PhD
Cincinnati Children's Hospital Medical Center
PLK1, a potential novel therapeutic target for lupus
Tianfu Wu, PhD
University of Houston
2014 Funded Grants
Therapeutic potential of sialylated IgG Fc in SLE
Robert Anthony, PhD
Massachusetts General Hospital, Harvard Medical School
Iron and ER stress in lupus nephritis
Erika Boesen, PhD
Nebraska Medical Center
Identification of lupus causal variants at 8p23.1 by mapping 3D genome
Iouri Chepelev, PhD
Cincinnati Children's Hospital Medical Center
Altered renal circadian rhythm in SLE nephritis
Anne Davidson, MBBS
Molecular Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell and Feinstein Institutes for Medical Research
The role of the long non-coding RNA lincRNA-Eps in lupus
Katherine Fitzgerald, PhD
University of Massachusetts Medical School
CD244 targeting therapeutics in SLE
Edith Janssen, PhD
Cincinnati Children's Hospital Medical Center
A role for diet-sensitive gut commensals in systemic autoimmunity
Martin Kriegel, MD, PhD
Yale School of Medicine
CD19-targeted cytotoxic T cells for lupus therapy
Marko Radic, PhD
University of Tennessee, Memphis
Tissue sodium in autoimmune disease
Michael Stein, MBChB
Vanderbilt University Medical Center
The OX40L-OX40 axis in lupus pathogenesis
Hideki Ueno, MD, PhD
Mount Sinai School of Medicine
Single cell detection of IFN signaling in lupus patients
Mark Walter, PhD
University of Alabama at Birmingham
2013 Funded Grants
RIG-I regulation of interferon signature in SLE
Ralph Budd, MD
The University of Vermont Medical Center
Mitochondrial autophagy in the control of systemic autoimmunity
Min Chen, PhD
Baylor College of Medicine
Autoantibodies and prolactin participate in a positive feedback loop
Betty Diamond, MD
The Feinstein Institute for Medical Research and Donald and Barbara Zucker School of Medicine at Hofstra/Northwell
Cutaneous and systemic lupus induced by UVB
Keith Elkon, MD
University of Washington
Innate immune cell mechanisms controlling inflammation in Systemic Lupus Erythematosus
Hans Haecker, MD PhD
University of Utah, School of Medicine
Mechanisms and consequences of HDL small RNA communication in SLE
Amy Major, PhD
Vanderbilt University Medical Center
TWEAK/Fn14 pathway in the pathogenesis & treatment of neuropsychiatric SLE
Chaim Putterman, MD
Albert Einstein College of Medicine
Function of SLE-related regulatory regions of human A20/TNFAIP3 gene
Gong Shiaoching, PhD
Weill Cornell Medical College
Novel treatments for lupus nephritis
Joshua Thurman, MD
University of Colorado Denver, AMC and DC
Bone marrow stem cell niche dysfunction in human SLE
Lijun Yang, MD
University of Florida
2012 Funded Grants
Biological role of FCRL molecules in SLE pathogenesis
Randall Davis, MD
The University of Alabama at Birmingham
Molecular basis and novel therapy of systemic lupus-associated thrombosis
Bruce Furie, MD
Beth Israel Deaconess Medical Center
Sex hormones, dendritic cells, and the IFN signature in lupus
Stefania Gallucci, MD
Temple University
Hes1 as a novel regulator of the type I interferon pathway in SLE
Xiaoyu Hu, MD, PhD
The Hospital for Special Surgery
Regulation of SLE through SOCS1 mimetic peptides
Joe Larkin, PhD
University of Florida
Exploring the role of interferon kappa in SLE pathogenesis
Deborah Lenschow, MD, PhD
Washington University in St.Louis
Linking ABIN-1 to SLE susceptibility
Averil Ma, MD
The Regents of the University of California, San Francisco
Novel insights into cerebral lupus
Chandra Mohan, MD, PhD
University of Houston
Dual reactive B cells in murine and human SLE
Roberta Pelanda, PhD
University of Colorado Anschutz School of Medicine
Activation of iRhom2/ADAM17/HB-EGF/EGFR pathway in immune complex nephritis
Jane Salmon, MD
The Hospital for Special Surgery
The microbiome and SLE
Gregg Silverman, MD
New York University School of Medicine
Learning from viruses how to suppress type I interferons to cure lupus
Elina Zuniga, PhD
The Regents of the University of California, San Diego