Top Research Needs to Help Kids with Lupus
July 5, 2019 A study published last week in Pediatric Rheumatology identified the top priorities for research into lupus in children. The survey asked pediatric rheumatologists, dermatologists and nephrologists with expertise in lupus to categorize areas of research into high, medium or low priority. The survey was given to pediatric rheumatologists, dermatologists and nephrologists with […]
Lupus Study Showed Vitamin D Did Not Improve Bone Health
September 19, 2019 A small clinical trial published in Lupus Science & Medicine found that taking vitamin D supplements did not improve bone health for people with lupus. Conducted by several lupus experts throughout the U.S., the study looked at the effect of vitamin D supplements on changes in bone turnover markers that indicate changes […]
Lupus News Corner
BIG … BOLD … IDEAS ARE TRANSFORMING LUPUS RESEARCH—thanks to people like you! Thanks to our remarkable supporters, the Lupus Research Alliance awarded nearly $7.5 million through the following grant mechanisms in 2019: 2019 Novel Research Grants ($1,798,602) Carla Cuda, PhD The Role of Microglial Subsets in Driving Neuropsychiatric Symptoms of SLE Northwestern University – Chicago […]
Positive Research Results on Potential Lupus Treatments Shared at Major Medical Meeting
June 8, 2021 The annual European Congress of Rheumatology (EULAR 2021) brought much good news of potential new treatments for systemic lupus erythematosus (SLE). Following are highlights: Rituximab Plus Belimumab Taking belimumab after rituximab may help lupus according to data from the BEAT-LUPUS trial presented at the 2021 EULAR Virtual Congress by the trial lead investigator […]
Stelara® and Olumiant® Considered Promising by Lupus Expert
February 19, 2019 In Healio Rheumatology, Dr. Gregg Silverman, professor of medicine and pathology at NYU School of Medicine, provided an overview of potential lupus therapies in development. He highlighted ustekinumab (brand name Stelara®) and baricitinib (brand name Olumiant®) as two drugs that look particularly promising. “The phase 2 extra-renal trial of baricitinib looks good; […]
About Lupus
A chronic and complex autoimmune disease, lupus can affect any part of the body causing widespread inflammation and tissue damage in the affected organ. The most commonly impacted areas are the joints, skin, brain, lungs, kidneys and blood vessels. Here are some basic facts about the disease, its symptoms, diagnosis and treatment.
LRA Congratulates Equillium on Positive Results of Study of Potential New Lupus Treatment
March 30, 2021 Equillium, Inc. announced positive topline data from the phase 1b EQUALISE study in patients with systemic lupus erythematosus (SLE). This study suggests that itolizumab, a monoclonal antibody selectively targeting the CD6-ALCAM pathway, was safe and well tolerated among people with SLE. [Source: Equillium, Inc. Press Release 3.30.21] The EQUALISE study is evaluating […]
Have You Thought About a Lupus Clinical Trial as a Treatment Option?
January 16, 2020 With so few current treatment options for lupus and lupus nephritis, patients may benefit from joining a clinical study. Right now, five national trials are testing interventions for lupus nephritis that you may be able to join. To learn more about these and over 150 other trials for lupus and its many […]
Lupus Research Turns Immune System Enemies into Friends
Jan. 17, 2018 Lupus Research Turns Immune System Enemies into Friends With support from a Lupus Research Alliance Novel Research Grant, Robert Anthony, PhD, made a groundbreaking discovery that could lead to a new, effective treatment of lupus and other autoimmune diseases. At Massachusetts General Hospital and Harvard Medical School, Dr. Anthony successfully turned autoimmune […]
Lupus Kidneys Copy Tumors’ Tactic to Protect Themselves
October 4, 2018 Abnormal immune cells invade the kidneys in patients with lupus and can damage the organs so severely that they stop working. But the kidneys defend themselves from these attacks by disabling these rogue cells, according to a new study from two scientists funded by the Lupus Research Alliance. Cancerous tumors similarly protect […]