LRA Congratulates Aurinia on Published Results with FDA-Approved Lupkynis™
May 10, 2021 The highly prestigious medical journal The Lancet published the results of Aurinia’s Phase 3 AURORA 1 study testing Lupkynis™ (voclosporin) in adults with lupus nephritis. Lupkynis was approved by the U.S. Food and Drug Administration based on these data. The AURORA 1 study results showed that Lupkynis in combination with the commonly used […]
Global Team Science Award
The Global Team Science Award ($3 million over three years) will support collaborative, and highly synergistic projects by international, multidisciplinary teams that push the boundaries of innovation to bridge research and clinical initiatives in lupus. 2023 Funded Grants Identifying Genetic and Immunological Determinants of Childhood Lupus Nephritis Elena Hsieh, M.D., Jean-Laurent Casanova, M.D., Ph.D., Debashis […]
Ferroptosis
The term ferroptosis is derived from the Greek word ptosis, meaning “a fall,” and ferrum, the Latin word for iron. It describes a form of regulated cell death in which iron appears to be a factor. Many lupus experts believe that ferroptosis may play an important role in lupus nephritis.
Edema
Edema means swelling caused by excess fluid in the body’s tissues. It usually occurs in the feet, ankles and legs, but it can involve the entire body. Edema can be a symptom of lupus nephritis. Source: MedlinePlus.gov, NIH.gov
Electrolytes
Electrolytes are minerals in your body that have an electric charge. They are in your blood, urine and body fluids. Maintaining the right balance of electrolytes helps your body’s blood chemistry, muscle action and other processes. Sodium, calcium, potassium, chlorine, phosphate and magnesium are all electrolytes. You get them from the foods you eat and […]
Kidney
Your kidneys are two bean-shaped organs, each about the size of your fists. They are located near the middle of your back, just below the rib cage. Inside each kidney about a million tiny structures called nephrons filter blood. They remove waste products and extra water, which become urine. The urine flows through tubes called […]